HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4,4-Difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-methanone → HCID 73013561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4,4-Difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridin-2-yl]-methanone | HCID 16727356 | — |
| Reactant | HCID 73013558 | HCID 73013558 | — |
| Product | HCID 73013561 | HCID 73013561 | — |
Reaction Steps
The title compound was synthesized in analogy to example 9, intermediate b), through hydrogenation of 5-benzyloxy-6-chloro-pyrrolo[2,3-b]pyridine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester to give the compound as a white solid (62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07622466B2 |
| Source dataset | uspto-grants-2009_11 |
| ORD ID | ord-5309f6e5a4df479d9514ed8e73b49e3a |
| Source note | uspto-grants-2009_11 |