Glycolide → HCID 6453016, compound

Participants

Reaction Steps

An operation was conducted in the same manner as in Example 13 except that 22,050 g (glycolic acid: 70 ppm, glycolic acid dimer: 360 ppm, water: 20 ppm; overall proton concentration of impurities: 0.054 mol %) of glycolide and 450 g (lactic acid: 0 ppm, lactic acid dimer: 270 ppm, water: 8 ppm; overall proton concentration of impurities: 0.030 mol %) of L-lactide were used, and 2.06 g [in view of the amount (0.36 g) of water (moisture) contained in an atmosphere within the container] of water were added to control the overall proton concentration (set proton concentration) to 0.124 mol %. After completion of the polymerization, the yield of bulk matter of a poly(glycolic acid/L-lactic acid) copolymer formed was almost 100%. The bulk matter was ground by a grinder, and the physical properties of the ground product were measured. The results are shown in Table 5.

Provenance & Evidence