4-[4-(Pyridin-2-ylsulfanylcarbonyl)-butyl]-piperidine-1-carboxylic acid tert-butyl ester → 4-(5-Cyclopentyl-5-oxo-pentyl)-piperidine-1-carboxylic acid tert-butyl ester

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Reaction Steps

The title compound was prepared analogously to step 7 of example B(29) where 4-[4-(pyridin-2-ylsulfanylcarbonyl)-butyl]-piperidine-1-carboxylic acid tert-butyl ester from step 5 above, was substituted in place 3-cyclohexyl-thiopropionic acid S-pyridin-2-yl ester. 1H NMR (400 MHz, CDCl3): δ 1-1.42 (m, 8H), 1.45 (s, 9H), 1.50-1.84 (m, 14H), 2.42-2.46 (m, 2H), 2.62-2.7 (m, 2H), 2.82-2.87 (m, 1H). ESIMS (MH+): 337.

Provenance & Evidence