1-Butanol → HCID 136354593, compound

HRID 1438696Notes

Reaction equation

HRID 1438696 reaction equation
[OH:1][C:2]1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])[O:8][CH3:9].[CH2:15](O)[CH2:16][CH2:17]C>>[OH:1][C:2]1[C:3]2[CH:14]=[CH:13][CH:12]=[CH:11][C:4]=2[S:5][C:6]=1[C:7](=[NH:10])[O:8][CH2:9][CH2:15][CH2:16][CH3:17]

Participants

3

Reactant 2

HCID 2631-ButanolHCID 304079852947-34-9

Product 1

HCID 136354593HCID 136354593, compound

Procedure

A solution of 12 g of methyl 3-hydroxy-benzo[b]thiphene-2-carboximidate (Example 1) in 300 m. of anhydrous n-butanol is heated under reflux for 4 hours and then concentrated to yield upon crystallization from ethyl acetate solution yellow crystals having an m.p. of 185° C.

Workup

  1. temperatureunder reflux for 4 hours
  2. concentrationconcentrated
  3. customto yield upon crystallization from ethyl acetate solution yellow crystals

Sources & evidence

ORD record
ord-1cc4a1ca335c486fbc1f5ded382b0e83
Source dataset
uspto-grants-1977_11
Patent number
US04056526

Reaction notes

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