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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1438716Generated: October 25, 2026

Ethyl propiolate → 1-(4-Chloro-benzyl)-pyrazol-5-one

https://huagongshe.com/reaction/1438716

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl propiolateHCID 12182—
Reactant(4-Chlorobenzyl)hydrazineHCID 3015209—
Solvent1-ButanolHCID 263—
Product1-(4-Chloro-benzyl)-pyrazol-5-oneHCID 23334250—

Reaction Steps

9.8 g (0.1 mol) of propiolic acid ethyl ester and 15.6 g (0.1 mol) of p-chlorobenzylhydrazine in 100 ml of n-butanol were heated for 8 hours under reflux.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04056533
Source datasetuspto-grants-1977_11
ORD IDord-d2efeb776f954a50bc01176eddbbda63
Source noteuspto-grants-1977_11