Hydrochloric Acid → (6-Chloro-2-oxohexyl) triphenylphosphonium chloride

HRID 1438828Notes

Reaction equation

HRID 1438828 reaction equation
[Cl-:1].[O:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C:3]1=[CH:8][P+:9]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.Cl>>[Cl-:1].[Cl:1][CH2:7][CH2:6][CH2:5][CH2:4][C:3](=[O:2])[CH2:8][P+:9]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 73680070[(tetrahydro-2H-pyran-2-ylidene)methyl]triphenylphosphonium chloride

Product 1

HCID 20526427(6-Chloro-2-oxohexyl) triphenylphosphonium chloride

Procedure

A solution consisting of 18.5 parts of [(tetrahydro-2H-pyran-2-ylidene)methyl]triphenylphosphonium chloride in 100 parts by volume of concentrated hydrochloric acid is heated at the reflux temperature for about 36 hours, then is cooled to room temperature. The solvent is removed by distillation under reduced pressure to afford (6-chloro-2-oxohexyl)triphenylphosphonium chloride, identical with the product of Example 2.

Workup

  1. temperatureis heated at the reflux temperature for about 36 hours
  2. customThe solvent is removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-52ea49462e964500a93ffe6fb16b3976
Source dataset
uspto-grants-1977_11
Patent number
US04056562

Reaction notes

Loading…