Methyl iodide → HCID 23050531, compound

Participants

Reaction Steps

66 ml of methyl iodide were added to a solution of 200 g of 4-amino-6-sec.-butyl-3-thioxo-1,2,4-triazin-5(2H,4H)-one in a solution of 40 g of sodium hydroxide in 1 liter of water, at 20° C, whilst stirring. When the slightly exothermic reaction had subsided, stirring was continued until the pH value reached 7 - 8 and the reaction product which had crystallized out was filtered off and washed with cold water. After drying, 205 g (96%) of 4-amino-6-sec.-butyl-3-methylthio-1,2,4-triazin-5(4H)-one were obtained, melting point 60° C (from carbon tetrachloride/petroleum ether).

Provenance & Evidence