HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester | HCID 53834251 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid | HCID 21322583 | — |
Reaction Steps
10 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester are dissolved in 50 ml. of ethanol and the solution is heated under reflux with 2 g. of KOH for 3 hours, evaporated and worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid, m.p. 121°-123°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057647 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-1e0f4250ab89497c96488a23b4cf1cd1 |
| Source note | uspto-grants-1977_11 |