HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid | HCID 21322583 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)-2-butenoic acid | HCID 54010068 | — |
Reaction Steps
1 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid is dissolved in 5 ml. of acetic acid. 1 ml. of concentrated hydrochloric acid is added and the mixture is allowed to stand for 2 hours at 20° and poured onto ice. After the customary work up, 3-(2',4'-difluoro-4-biphenylyl)-2-butenoic acid, m.p. 193°-195°, is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04057647 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-7485df1e7ebe4e5389b6f4c7ef2b4781 |
| Source note | uspto-grants-1977_11 |