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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439049Generated: October 30, 2026

3-(2',4'-Difluoro-4-biphenylyl)butyric acid ethyl ester → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid

https://huagongshe.com/reaction/1439049

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2',4'-Difluoro-4-biphenylyl)butyric acid ethyl esterHCID 54340187—
SolventWaterHCID 962—
Product3-(2',4'-Difluoro-4-biphenylyl)butyric acidHCID 21322540—

Reaction Steps

A mixture of 1 g. of 3-(2',4'-difluoro-4-biphenylyl)butyric acid ethyl ester and 100 ml. of water is heated to 180° in an autoclave for 24 hours. It is cooled and worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04057647
Source datasetuspto-grants-1977_11
ORD IDord-dc11eeb6e41745f5be9fb45598cb2e3c
Source noteuspto-grants-1977_11