HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(4-Chlorophenoxy)-1-methyl-3,5-diphenyl-1H-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-[(1-Methyl-3,5-diphenyl-1H-pyrazol-4-yl)oxy]aniline | HCID 21398101 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(4-Chlorophenoxy)-1-methyl-3,5-diphenyl-1H-pyrazole | HCID 21398087 | — |
Reaction Steps
A solution of sodium nitrite (3.1 g, 0.0422 mole) in water (10 ml) is added slowly at 0° C to 5° C to a well stirred, chilled solution of 4-(p-aminophenoxy)-1-methyl-3,5-diphenylpyrazole (15.1 g, 0.0442 mole) in concentrated hydrochloric acid (50 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04058391 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-72ddf36afaad4156b4a6aa9ced54660c |
| Source note | uspto-grants-1977_11 |