Methane → HCID 21398374, compound

Participants

Reaction Steps

19.2 Parts of 4-benzoyl-butyric acid and 9 parts of 1,3-propanediamine are heated for 21/2 hours at 150°-160°. The reaction mixture is cooled to about 60°, extracted with hot ethyl acetate and the solution obtained is clarified over charcoal. On concentrating, the reaction product precipitates and is purified by recrystallisation from ethyl acetate. The melting point of the 9a-phenyl-octahydro-6H-pyrido[1,2-a]pyrimidin -6-one of the formula ##STR34## obtained is 142.5°. The following compound is obtained in an analogous manner:

Provenance & Evidence