Diethylamine → HCID 21396817, compound

Participants

Reaction Steps

In the manner of Example II B, 8.4 g of phenyl (3-ethoxy-4-ethoxycarbonyl-5-isothiazolyl)carbamate in 20 ml of dimethylformamide were allowed to react with 3.7 g of diethylamine. The solid from the reaction mixture was recrystallized from ethanol:water (70:30) to give 3.2 g of 1,1-diethyl-3-(3-ethoxy-4-ethoxycarbonyl-5-isothiazolyl)urea, m.p. 77°-80°. The nmr spectrum was consistent with the assigned structure.

Provenance & Evidence