Acrolein → 3-(Butylthio)propionaldehyde
Reaction equation
[CH2:1]([SH:5])[CH2:2][CH2:3][CH3:4].[CH:6]([CH:8]=[CH2:9])=[O:7]>N1CCCCC1>[CH2:1]([S:5][CH2:9][CH2:8][CH:6]=[O:7])[CH2:2][CH2:3][CH3:4]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 0.5 °C
Procedure
A mixture of butylmercaptan (180 g) and piperidine (1 drop) was cooled to 0.5° C in a flask equipped with a stirrer, dropping funnel, thermometer pocket and vent pipe and acrolein (112 g) was added dropwise over a period of 2-3 hours at such a rate as to maintain the temperature at less than 15° C. After all the acrolein had been added, the mixture was stirred for a further 20-24 hours, and the resulting mixture was taken as product (100% yield).
Workup
- customequipped with a stirrer
- temperatureto maintain the temperature at less than 15° C
Sources & evidence
- ORD record
- ord-1e271e560e0f45d2b96c25d1ca6f2f04
- Source dataset
- uspto-grants-1977_11
- Patent number
- US04059569
Reaction notes
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