Methylparaben → HCID 22764888, compound

HRID 1439414Notes

Reaction equation

HRID 1439414 reaction equation
[CH3:1][O:2][C:3](=[O:11])[C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.[NH:12]([C:17]([O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:18])[CH2:13][C:14](O)=[O:15]>>[CH3:1][O:2][C:3]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:14](=[O:15])[CH2:13][NH:12][C:17]([O:19][CH2:20][C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)=[O:18])=[CH:6][CH:5]=1)=[O:11]

Participants

3

Reactant 2

HCID 7456MethylparabenHCID 14349Benzyloxycarbonylglycine

Product 1

HCID 22764888HCID 22764888, compoundYield 70%

Procedure

p-Hydroxybenzoic methyl ester and Z-Gly.OH were treated in the same manner as in Example 78 to obtain N-benzyloxycarbonyl glycine p-methoxycarbonylphenyl ester (hereinafter represented by ##STR11## COOCH3 ") in a yield of 70%.

Workup

  1. additionOH were treated in the same manner as in Example 78

Sources & evidence

ORD record
ord-5115edb618ad42d5954bfa028730faaf
Source dataset
uspto-grants-1977_11
Patent number
US04059603

Reaction notes

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