HRID1439482

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7678

1-Phenylacetone

C9H10O

HCID2734109

1-(2-methylphenyl)propan-2-one

C10H12O

结构：CCCCCC(CCCC(CCCCCCC(=O)OCC)(C(C)=O)c1ccccc1C)OCc1ccccc1

HCID21397387

未命名化合物

PRODUCTS

生成物

结构：CCCCCC(O)CCCC(CCCCCCC(=O)O)(C(C)=O)c1ccccc1C

HCID21397403

未命名化合物

PROCEDURE

实验过程

By following the procedures described in Example 3, but substituting (2-methyphenyl)acetone for the phenylacetone employed in Step C, there are obtained successively from that point: 3-(2-methylphenyl)-7-benzyloxy-2-dodecanone (Step C); ethyl 8-acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoate (Step D); 8-acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoic acid (Step E); and 8-acetyl-(2-methylphenyl)-12-hydroxyheptadecanoic acid (Step F).

WORKUP

后处理

customare obtained successively from that point

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7b33bd9c257540ff978d67faf35ef3d5
来源数据集: uspto-grants-1977_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04059601
来源说明: uspto-grants-1977_11

反应 SMILES

CC1C=CC=CC=1CC(=O)C.C1(CC(=O)C)C=CC=CC=1.CC1C=CC=CC=1C(CCCC(OCC1C=CC=CC=1)CCCCC)C(=O)C.[C:50]([C:53]([C:82]1[CH:87]=[CH:86][CH:85]=[CH:84][C:83]=1[CH3:88])([CH2:65][CH2:66][CH2:67][CH:68]([O:74]CC1C=CC=CC=1)[CH2:69][CH2:70][CH2:71][CH2:72][CH3:73])[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][C:60]([O:62]CC)=[O:61])(=[O:52])[CH3:51].C(C(C1C=CC=CC=1C)(CCCC(OCC1C=CC=CC=1)CCCCC)CCCCCCC(O)=O)(=O)C.C(C(CCCC(O)CCCCC)CCCCCC(C1C=CC=CC=1C)C(O)=O)(=O)C>>[C:50]([C:53]([C:82]1[CH:87]=[CH:86][CH:85]=[CH:84][C:83]=1[CH3:88])([CH2:65][CH2:66][CH2:67][CH:68]([OH:74])[CH2:69][CH2:70][CH2:71][CH2:72][CH3:73])[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][C:60]([OH:62])=[O:61])(=[O:52])[CH3:51]