HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetone → 8-Acetyl-8-(2-methylphenyl)-12-hydroxyheptadecanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetone | HCID 7678 | — |
| Reactant | 1-(2-Methylphenyl)propan-2-one | HCID 2734109 | — |
| Reactant | Ethyl 8-acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoate | HCID 21397387 | — |
| Reactant | 8-Acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoic acid | HCID 21397391 | — |
| Reactant | 8-Acetyl-(2-methylphenyl)-12-hydroxyheptadecanoic acid | HCID 21397404 | — |
| Reactant | 3-(2-Methylphenyl)-7-benzyloxy-2-dodecanone | HCID 21397413 | — |
| Product | 8-Acetyl-8-(2-methylphenyl)-12-hydroxyheptadecanoic Acid | HCID 21397403 | — |
Reaction Steps
By following the procedures described in Example 3, but substituting (2-methyphenyl)acetone for the phenylacetone employed in Step C, there are obtained successively from that point: 3-(2-methylphenyl)-7-benzyloxy-2-dodecanone (Step C); ethyl 8-acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoate (Step D); 8-acetyl-8-(2-methylphenyl)-12-benzyloxyheptadecanoic acid (Step E); and 8-acetyl-(2-methylphenyl)-12-hydroxyheptadecanoic acid (Step F).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04059601 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-7b33bd9c257540ff978d67faf35ef3d5 |
| Source note | uspto-grants-1977_11 |