Hydrochloric Acid → HCID 178486336, compound

HRID 1439512Notes

Reaction equation

HRID 1439512 reaction equation
[C:1]([C:9]1[C:18]([CH2:19][OH:20])=[N+:17]([O-:21])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N+:10]=1[O-:22])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:24]O>>[CH3:24][O:8][C:1]1([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:9]2=[N+:10]([O-:22])[C:11]3[C:16]([N+:17]([O-:21])=[C:18]2[CH2:19][O:20]1)=[CH:15][CH:14]=[CH:13][CH:12]=3

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 178519483HCID 178519483, compound

Product 1

HCID 178486336HCID 178486336, compoundYield 60%

Procedure

A stirred suspension of 0.25 g. (0.84 mmol.) of 2-benzoyl-3-hydroxymethylquinoxaline 1,4-dioxide, in 10 ml. of methanol, was saturated with dry hydrogen chloride. The reaction mixture was stirred at room temperature overnight and then the suspended solid was collected by filtration. This afforded 0.16 g. (60% yield) of 1-methoxy-1-phenyl-1,3-dihydrofuro[3,4-b]quinoxaline 4,9-dioxide, m.p. 150°-151° C.

Workup

  1. additionA stirred suspension of 0.25 g
  2. filtrationthe suspended solid was collected by filtration

Sources & evidence

ORD record
ord-246ceec01497456e93cb907f7a388b24
Source dataset
uspto-grants-1977_11
Patent number
US04060523

Reaction notes

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