Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | Methanone, (3-methyl-1,4-dioxido-2-quinoxalinyl)phenyl- | HCID 178428812 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178519460 | HCID 178519460 | 85% |
Reaction Steps
To a stirred suspension of 28 g. (0.10 mol.) of 2-benzoyl-3-methylquinoxaline 1,4-dioxide in 1,000 ml. of methanol was added 5.6 ml. (0.11 mol.) of bromine. The reaction mixture was refluxed for 2 hours and then an additional 5.6 ml. (0.11 mol.) of bromine was added. The mixture was refluxed for an additional 2 hours and then it was cooled to 25° C. The solid which had precipitated was collected by filtration, washed with methanol, and dried to affored 30.4 g. (85% yield) of 2-benzoyl-3-bromomethylquinoxaline 1,4-dioxide, m.p. 183°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04060523 |
|---|
| Source dataset | uspto-grants-1977_11 |
|---|
| ORD ID | ord-0568a3dd632d4e23865470e76a10dec1 |
|---|
| Source note | uspto-grants-1977_11 |
|---|
