反应详情

To a stirred solution of 28.2 parts of p-(2-thenoyl)hydratropic acid, sodium salt in 250 parts of hexamethylphosphoramide are added 49.2 parts of 1-bromopropane and the whole is stirred for 2 hours at room temperature. The reaction mixture is poured onto 1000 parts of water and the product is extracted three times with diisopropylether. The combined extracts are washed with 200 parts of water, dried, filtered and evaporated. The viscous residue is filtered off over hyflo, yielding propyl p-(2-thenoyl)hydratropate as a yellow oil.

1. extractionthe product is extracted three times with diisopropylether
2. washThe combined extracts are washed with 200 parts of water
3. customdried
4. filtrationfiltered
5. customevaporated
6. filtrationThe viscous residue is filtered off over hyflo