HCID 21396264, compound → HCID 21396260, compound

HRID 1439717Notes

Reaction equation

HRID 1439717 reaction equation
[C:1]([O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16]Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(#N)C.C([O-])(=O)C.[Ag+]>[C:1]([O:9][CH2:16][O:15][CH2:14][CH2:13][O:12][CH2:11][CH2:10][O:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:8])[CH3:2]

Participants

4

Reactant 1

HCID 21396264HCID 21396264, compound

Product 1

HCID 21396260HCID 21396260, compoundYield 194.6%

Reagents, catalysts & solvents 2

HCID 11246Silver acetateCatalystHCID 6342AcetonitrileSolvent

Procedure

Silver acetate (3.34 g) was added with cooling and stirring to a solution of 2-(2-benzoyloxyethoxy)ethoxymethyl chloride (5.18 g) in dry acetonitrile (15 ml). The reaction mixture was stirred overnight at room temperature. The precipitate was removed by filtration and the filtrated evaporated under reduced pressure at 35° C. to give 2-(2-benzoyloxyethoxy)ethoxymethyl acetate (5.5 g) as a pale yellow oil. NMR and IR spectra were consistent with this structure.

Workup

  1. temperaturewith cooling
  2. customThe precipitate was removed by filtration
  3. customthe filtrated evaporated under reduced pressure at 35° C.

Sources & evidence

ORD record
ord-5b469dfa574741a0b93ae9fb45bb9874
Source dataset
uspto-grants-1977_11
Patent number
US04060616

Reaction notes

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