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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439730Generated: October 30, 2026

2-Chloro-4-hydrazino-6,7-dimethoxyquinazoline → 4-Hydrazino-2-[4-(cyclopentylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazolinehydrochloride

https://huagongshe.com/reaction/1439730

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-hydrazino-6,7-dimethoxyquinazolineHCID 64030—
Reactant1-CyclopentanecarbonylpiperazineHCID 15512779—
Product4-Hydrazino-2-[4-(cyclopentylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazolinehydrochlorideHCID 21183929—

Reaction Steps

N-(Cyclopentylcarbonyl)piperazine (0.02 mole) and 2-chloro-4-hydrazino-6,7-dimethoxyquinazoline (0.02 mole) reacted according to the procedure of Example 7 provides 4-hydrazino-2-[4-(cyclopentylcarbonyl)-1-piperazinyl]-6,7-dimethoxyquinazolinehydrochloride, m.p. 282°-284° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04060615
Source datasetuspto-grants-1977_11
ORD IDord-d5f7655241924a1b8cba8a1069df4a98
Source noteuspto-grants-1977_11