7-Aminocephalosporanic acid → HCID 70604275, compound

HRID 1439735Notes

Reaction equation

HRID 1439735 reaction equation
[Na].[C:2]([CH2:7][C:8]1[N:12]=[C:11]([SH:13])[NH:10][N:9]=1)([O:4][CH2:5][CH3:6])=[O:3].CC(O[CH2:18][C:19]1[CH2:28][S:27][C@@H:22]2[C@H:23]([NH2:26])[C:24](=[O:25])[N:21]2[C:20]=1[C:29]([OH:31])=[O:30])=O>>[NH2:26][CH:23]1[C:24](=[O:25])[N:21]2[C:20]([C:29]([OH:31])=[O:30])=[C:19]([CH2:18][S:13][C:11]3[N:12]=[C:8]([CH2:7][C:2]([O:4][CH2:5][CH3:6])=[O:3])[NH:9][N:10]=3)[CH2:28][S:27][C@H:22]12

Participants

3

Reactant 2

HCID 4413287-Aminocephalosporanic acidHCID 178470799HCID 178470799, compound

Product 1

HCID 70604275HCID 70604275, compound

Procedure

Reaction of 3-carbethoxymethyl-1,2,4-triazole-5-thiol sodium salt, prepared as described in Example 8, and 7-aminocephalosporanic acid according to the procedure described in Example 8 gives the title compound.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-a85a1760721c4e7a90a8ce187cd52656
Source dataset
uspto-grants-1977_11
Patent number
US04060610

Reaction notes

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