7-Aminocephalosporanic acid → HCID 178508103, compound

HRID 1439741Notes

Reaction equation

HRID 1439741 reaction equation
[Na].[Na].[C:3]([CH2:6][CH2:7][C:8]1[N:9]=[N:10][NH:11][C:12]=1[SH:13])([OH:5])=[O:4].CC(O[CH2:18][C:19]1[CH2:28][S:27][C@@H:22]2[C@H:23]([NH2:26])[C:24](=[O:25])[N:21]2[C:20]=1[C:29]([OH:31])=[O:30])=O>>[NH2:26][CH:23]1[C:24](=[O:25])[N:21]2[C:20]([C:29]([OH:31])=[O:30])=[C:19]([CH2:18][S:13][C:12]3[NH:11][N:10]=[N:9][C:8]=3[CH2:7][CH2:6][C:3]([OH:5])=[O:4])[CH2:28][S:27][C@H:22]12

Participants

3

Reactant 2

HCID 4413287-Aminocephalosporanic acidHCID 178525377HCID 178525377, compound

Product 1

HCID 178508103HCID 178508103, compound

Procedure

When an equivalent amount of 4-(2-carboxyethyl)-1,2,3-triazol-5-thiol disodium salt, prepared as in Example 8, is reacted with 7-aminocephalosporanic acid by the procedure of Example 8, 7-amino-3-[4-(2-carboxyethyl)-1,2,3-triazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid is obtained.

Sources & evidence

ORD record
ord-e132ba7672d14173a9136c380c1e8708
Source dataset
uspto-grants-1977_11
Patent number
US04060610

Reaction notes

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