反应详情

A solution of 2-(4-aminobutyl)pyridine (2.9 g) and S-methyl-N-nitroisothiourea (2.9 g) in methanol (50 ml) was heated at 50-65° for 4-5 hours. Concentration, followed by recrystallisation of the residue yielded N-[4-(2-pyridyl)butyl]-N'-nitroguanidine.

1. concentrationConcentration
2. customfollowed by recrystallisation of the residue