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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1439746Generated: October 30, 2026

HCID 12951531, compound → N-benzenesulphonyl-N"-[2-((3-methyl-2-pyridyl)methylthio)ethyl]guanidine

https://huagongshe.com/reaction/1439746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12951531HCID 12951531—
ReactantHCID 178504065HCID 178504065—
SolventAcetonitrileHCID 6342—
ProductN-benzenesulphonyl-N"-[2-((3-methyl-2-pyridyl)methylthio)ethyl]guanidineHCID 21396300—

Reaction Steps

A solution of 3-methyl-2-((2-aminoethyl)thiomethyl)pyridine (6.3 g) and N-benzenesulphonyl-S-methylisothiourea (8.0 g) in acetonitrile (100 ml) was heated under reflux for 24 hours. Concentration, followed by chromatographic purification on a column of silica gel and recrystallisation afforded N-benzenesulphonyl-N"-[2-((3-methyl-2-pyridyl)methylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04060621
Source datasetuspto-grants-1977_11
ORD IDord-d8563523f475455594c72cecf5b78e48
Source noteuspto-grants-1977_11