Hydrochloric Acid → HCID 178485115, compound

HRID 1439748Notes

Reaction equation

HRID 1439748 reaction equation
[C:1]([NH:3][C:4]([NH:17]C)=[N:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[C:15]([OH:16])=[CH:14][CH:13]=[CH:12][N:11]=1)#N.[ClH:19]>>[ClH:19].[ClH:19].[CH3:1][NH:3][C:4]([NH2:17])=[N:5][CH2:6][CH2:7][S:8][CH2:9][C:10]1[C:15]([OH:16])=[CH:14][CH:13]=[CH:12][N:11]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178484994HCID 178484994, compound

Product 1

HCID 178485115HCID 178485115, compound

Procedure

A solution of N-cyano-N'-methyl-N"-[2-((3-hydroxy-2-pyridyl)-methylthio)ethyl]guanidine (2.2 g) in hydrochloric acid (25 ml) was heated on the steam bath for 2 hours. Concentration followed by recrystallisation of the product afforded N-methyl-N"-[2-((3-hydroxy-2-pyridyl)methylthio)ethyl]guanidine dihydrochloride (1.6 g).

Workup

  1. concentrationConcentration
  2. customfollowed by recrystallisation of the product

Sources & evidence

ORD record
ord-6a3f224a1ddf465f8a2fabc93729a92e
Source dataset
uspto-grants-1977_11
Patent number
US04060621

Reaction notes

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