HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → HCID 21396507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Reactant | 1-Chloro-3-(4'-fluoro-4-biphenylyl)-butan-3-ol | HCID 20302896 | — |
| Solvent | Diethylene Glycol | HCID 8117 | — |
| Product | HCID 21396507 | HCID 21396507 | — |
Reaction Steps
A mixture of 27.9 g. of 1-chloro-3-(4'-fluoro-4-biphenylyl)-butan-3-ol, 8.7 g. of KF, 10 ml. of ethylene glycol and 5 ml. of diethylene glycol is heated to 140° - 150° for 8 hours. It is cooled and worked up in the customary manner and gives 1-fluoro-3-(4'-fluoro-4-biphenylyl)-butan-3-ol, m.p. 90° - 92°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04060633 |
| Source dataset | uspto-grants-1977_11 |
| ORD ID | ord-670ec53042604fe69402d0bc91ee2e7c |
| Source note | uspto-grants-1977_11 |