Chlorine → 1-Cyano-3-(4-p-chlorophenoxy-phenyl)-butan-3-ol

Participants

Reaction Steps

2.76 g. of 1-cyano-3-(4-phenoxy-phenyl)-butan-3-ol are dissolved in 20 ml. of acetic acid, a solution of 0.8 g. of chlorine in 20 ml. of acetic acid is added dropwise at 20° while stirring, the mixture is stirred for a further one hour and evaporated and the residue is worked up in the customary manner to give 1-cyano-3-(4-p-chlorophenoxy-phenyl)-butan-3-ol, m.p. 68° - 70°.

Provenance & Evidence