Alanine methyl ester hydrochloride → HCID 21967976, compound

HRID 1440071Notes

Reaction equation

HRID 1440071 reaction equation
[C:1]([S:4][CH2:5][CH:6]([CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7](Cl)=[O:8])(=[O:3])[CH3:2].Cl.[NH2:18][C@H:19]([C:21]([O:23][CH3:24])=[O:22])[CH3:20]>C(N(CC)CC)C>[C:1]([S:4][CH2:5][CH:6]([CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:7]([NH:18][C@H:19]([C:21]([O:23][CH3:24])=[O:22])[CH3:20])=[O:8])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 2733257Alanine methyl ester hydrochlorideHCID 103777342-Acetylthiomethyl-3-phenyl-propionyl chloride

Product 1

HCID 21967976HCID 21967976, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

3-Acetylthio-2-benzylpropanoyl chloride and (L)-alanine, methyl ester, hydrochloride are reacted in the presence of triethylamine according to the procedure of Example 25 to give (±)-N-[2-(acetyl-thiomethyl) -1-oxo-3-phenylpropyl]-L-alanine, methyl ester.

Sources & evidence

ORD record
ord-5e0a1c4a7d984ce5b7ef9c5e6faf341e
Source dataset
uspto-grants-1996_03
Patent number
US05496805

Reaction notes

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