2-Tert-Butylphenol → HCID 10935541, compound

Participants

Reaction Conditions

Reaction Steps

99 g (0.5 mol) of diethyl phenylphosphonite and 75 g (0.5 mol) of 2-tert-butylphenol were mixed and heated with stirring at 530mbar to 170° C. Ethanol distilled off during this via a small column. The temperature was then increased stepwise to 180° C., and the vacuum was simultaneously enhanced to 100mbar. After 16 hours, a total of 18 g of ethanol distilled off. The batch was then cooled and distilled. After a first fraction, which contained the unreacted starting materials, 116 g were obtained having a boiling point of 139° C. at 0.1 mbar. The yield was thus for a 78% conversion rate almost 100% of theory.

Provenance & Evidence