Trimethyl phosphite → Dimethyl [(3-methylphenyl)methyl]phosphonate

HRID 1440668Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5]Br.[CH3:10][O:11][P:12]([O:15]C)[O:13][CH3:14]>>[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5][P:12](=[O:15])([O:13][CH3:14])[O:11][CH3:10]

Participants

Reactant 2

HCID 8472Trimethyl phosphite

HCID 12099m-Xylyl bromide

Product 1

HCID 2773781Dimethyl [(3-methylphenyl)methyl]phosphonate

Procedure

Following the procedure of Compound 11, 3-methylbenzyl bromide is reacted with trimethylphosphite.

Sources & evidence

ORD record: ord-31b4daa5304941c5b5d853962c6eb229
Source dataset: uspto-grants-1996_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05500417

Reaction notes

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