Benzene → 2-(Benzyloxy)-3-bromo-5-chloropyridine

HRID 144070Notes

Reaction equation

HRID 144070 reaction equation
[Ag+2:22].[Br:10][CH2:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1.[Br:1][c:2]1[c:3]([OH:9])[n:4][cH:5][c:6]([Cl:8])[cH:7]1.[C:18](=[O:19])([O-:20])[O-:21].[cH:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[Br:1][c:2]1[c:3]([O:9][CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[n:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

6

Reactant 5

HCID 241BenzeneHCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 178419107HCID 178419107, compoundHCID 178517755HCID 178517755, compound

Product 1

HCID 220583822-(Benzyloxy)-3-bromo-5-chloropyridine

Sources & evidence

ORD record
ord-f4876dc775e44df485337e847e799d74
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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