HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → Ethyl 2-(2-chlorobenzoyl)-3-dimethylaminopropenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | Ethyl (2-chlorobenzoyl)acetate | HCID 292405 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Ethyl 2-(2-chlorobenzoyl)-3-dimethylaminopropenoate | HCID 54509863 | 97.3% |
Reaction Steps
To a stirred solution of 5.0 g of ethyl 2-chlorobenzoylacetate in 50 cc of benzene was added dropwise 5 cc of dimethylformamide dimethylacetal in 15 cc of benzene at room temperature. The resulting mixture was heated under reflux for 6 hours. After cooling, the solvent was distilled off to obtain 6.2 g of compound D. Yield: 97.3%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05500424 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-76d15191124543359d0e65909b4cdb2b |
| Source note | uspto-grants-1996_03 |