反应详情

To a stirred solution of 5.0 g of ethyl 2-chlorobenzoylacetate in 50 cc of benzene was added dropwise 5 cc of dimethylformamide dimethylacetal in 15 cc of benzene at room temperature. The resulting mixture was heated under reflux for 6 hours. After cooling, the solvent was distilled off to obtain 6.2 g of compound D. Yield: 97.3%.

1. temperatureThe resulting mixture was heated
2. temperatureunder reflux for 6 hours
3. temperatureAfter cooling
4. distillationthe solvent was distilled off