HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Acetate → 2-(2-Chlorophenyl)-6-n-heptyl-3-pyridinecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | Ethyl 2-benzoyl-5-oxo-5-phenylvalerate | HCID 12015084 | — |
| Reactant | 2, 6-Diphenyl-3-pyridinecarboxylic acid ethyl ester | HCID 18981948 | — |
| Reactant | Ethyl 5-oxo-2-(2-chlorobenzoyl)laurate | HCID 18981976 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(2-Chlorophenyl)-6-n-heptyl-3-pyridinecarboxylic acid | HCID 18982019 | 70.6% |
Reaction Steps
A mixture of 0.90 g of compound I, 2.73 g of ammonium acetate and 2.80 g of ferric chloride hexahydrate in 20 cc of acetic acid was heated under reflux for 8 hours. Thereafter, 0.60 g of compound J was obtained in the same manner as in the production of compound H from compound G, Yield: 70.6%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05500424 |
| Source dataset | uspto-grants-1996_03 |
| ORD ID | ord-9b36d2650b6d4e548fba15a30ba98542 |
| Source note | uspto-grants-1996_03 |