Methanol → HCID 18982492, compound

HRID 1440918Notes

Reaction equation

HRID 1440918 reaction equation
[CH3:1][B-:2]([C:17]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=1)([C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1)[C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1.[Li+].F[P-](F)(F)(F)(F)F.[Cl:32][C:33]1[CH:38]=[CH:37][C:36]([S+:39]([C:51]2[CH:56]=[CH:55][C:54]([Cl:57])=[CH:53][CH:52]=2)[CH2:40][C:41]([C:43]2[CH:48]=[CH:47][C:46]([O:49][CH3:50])=[CH:45][CH:44]=2)=[O:42])=[CH:35][CH:34]=1.CO>C(#N)C>[Cl:57][C:54]1[CH:53]=[CH:52][C:51]([S+:39]([C:36]2[CH:35]=[CH:34][C:33]([Cl:32])=[CH:38][CH:37]=2)[CH2:40][C:41]([C:43]2[CH:48]=[CH:47][C:46]([O:49][CH3:50])=[CH:45][CH:44]=2)=[O:42])=[CH:56][CH:55]=1.[CH3:1][B-:2]([C:17]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=1)([C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1)[C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 18982326HCID 18982326, compoundHCID 88398139HCID 88398139, compound

Product 1

HCID 18982492HCID 18982492, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

A solution of 2.80 g of lithium methyl-tris(p-fluorophenyl)borate in 50 ml of acetonitrile was added to a solution of 5.00 g of bis(p-chlorophenyl)(p-methoxyphenacyl)sulfonium hexafluorophosphate in 100 ml of acetonitrile, and the resultant mixture was stirred at room temperature for 30 minutes. Then, 200 ml of methanol was added. The resultant precipitate of a crystal was recovered, and 100 ml of dichloromethane was added. The dichloromethane layer was washed with water, dried and concentrated to give 3.31 of bis(p-chlorophenyl)-(p-methoxyphenacyl)sulfonium-methyl-tris(p-fluorophenyl)borate.

Workup

  1. customThe resultant precipitate of a crystal was recovered
  2. addition100 ml of dichloromethane was added
  3. washThe dichloromethane layer was washed with water
  4. customdried
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-347a568390ad403cabe9e67823a52393
Source dataset
uspto-grants-1996_03
Patent number
US05500453

Reaction notes

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