Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68539905 | HCID 68539905 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68540965 | HCID 68540965 | — |
Reaction Steps
A mixture of (R)-2-(4-Boc-2-methylpiperazin-1-yl)acetamide (114 mg, 0.44 mmol) and 5N hydrochloric acid (0.2 ml) in 1,4-dioxane (2.0 ml) was stirred at 90° C. for 20 min. The mixture was concentrated in vacuo to afford (R)-2-(2-methylpiperazin-1-yl)acetamide hydrochloride salt quantitatively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07655645B2 |
|---|
| Source dataset | uspto-grants-2010_02 |
|---|
| ORD ID | ord-1fbf13db4ce44e3ab7267945123403c1 |
|---|
| Source note | uspto-grants-2010_02 |
|---|
