HCID 68697397, compound → HCID 68700878, compound

Participants

Reaction Steps

5.94 g 3-(2-chloro-5-nitro-phenyl)-7-methanesulfonyl-1-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one were dissolved in 200 mL tetrahydrofuran. Pd(CaCO3)/C was added to the solution which was then treated with hydrogen (1 atm) for 18 h. The solution was then filtrated and the solvent evaporated. The residue was extracted with diethyl ether and the title product obtained in 98% yield.

Provenance & Evidence