HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → N1-((tetrahydrofuran-3-yl)methyl)ethane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-(Chloromethyl)oxolane | HCID 23061577 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N1-((tetrahydrofuran-3-yl)methyl)ethane-1,2-diamine | HCID 59164401 | 77% |
Reaction Steps
A mixture of 0.2 mol of 3-(chloromethyl)tetrahydrofuran, 200 ml of ethanol, 0.2 mol of potassium carbonate and 0.2 mol of ethylenediamine placed in a 500 ml of round-bottomed flask was refluxed for 24 hours, and then the solvent was removed. The obtained product was yellow oily liquid in 77% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07655665B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-5fdd856e354d46dfba5da9b8842e0917 |
| Source note | uspto-grants-2010_02 |