Morpholine → 4-Morpholino-3-(trifluoromethyl)benzonitrile

HRID 1441736노트

반응식

HRID 1441736 반응식
Br[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1>>[N:14]1([C:2]2[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][C:3]=2[C:10]([F:13])([F:12])[F:11])[CH2:19][CH2:18][O:17][CH2:16][CH2:15]1

참가 물질

3

반응물 2

HCID 8083MorpholineHCID 108006474-Bromo-3-(trifluoromethyl)benzonitrile

생성물 1

HCID 595565444-Morpholino-3-(trifluoromethyl)benzonitrile

실험 절차

The title compound is prepared using an analogous method as described in Example 1.1, utilising 4-bromo-3-(trifluoromethyl)-benzonitrile and morpholine (Fluka, Buchs, Switzerland), with a reaction temperature of 95° C.

후처리

  1. customwith a reaction temperature of 95° C.

출처 및 근거

ORD 기록
ord-7bd2feddec2d40edbf537f11ebe57a31
출처 데이터셋
uspto-grants-2010_02
특허 번호
US07655669B2

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