Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1441746Generated: November 1, 2026

Imidazole → 3-(1H-imidazol-1-yl)-5-(trifluoromethyl)-benzonitrile

https://huagongshe.com/reaction/1441746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
Reactant3-Fluoro-5-(trifluoromethyl)benzonitrileHCID 519037—
Product3-(1H-imidazol-1-yl)-5-(trifluoromethyl)-benzonitrileHCID 68678866—

Reaction Steps

The title compound is prepared using an analogous method as described in Example 1.1, utilising 3-fluoro-5-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and imidazole (Fluka, Buchs, Switzerland), with a reaction temperature of 110° C. for 24 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07655669B2
Source datasetuspto-grants-2010_02
ORD IDord-d0dddc637c11435ba0650b48980c4ce9
Source noteuspto-grants-2010_02