1-Methylpiperazine → HCID 68676665, compound

HRID 1441749Notes

Reaction equation

HRID 1441749 reaction equation
F[C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=1)[C:5]#[N:6].[CH3:14][N:15]1[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1>>[CH3:14][N:15]1[CH2:20][CH2:19][N:18]([C:2]2[CH:3]=[C:4]([CH:7]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:9]=2)[C:5]#[N:6])[CH2:17][CH2:16]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 5190373-Fluoro-5-(trifluoromethyl)benzonitrile

Product 1

HCID 68676665HCID 68676665, compound

Procedure

The title compound is prepared using an analogous method as described in Example 1.1, utilising 3-fluoro-5-(trifluoromethyl)-benzonitrile (Lancaster Synthesis GmbH) and 1-methylpiperazine (Fluka, Buchs, Switzerland).

Sources & evidence

ORD record
ord-2e62f9e0e4894343a6f5626883f72c89
Source dataset
uspto-grants-2010_02
Patent number
US07655669B2

Reaction notes

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