1-Octanol → HCID 178443874, compound

Participants

Reaction Steps

In a 250 ml Schlenk flask, 58.75 g (0.381 moles) of diethyl sulfate was slowly added dropwise to 31.28 g (0.381 moles) of methylimidazole with ice cooling and under a blanket gas. Stirring of the mixture was continued at room temperature over night. After the addition of 62.72 g (0.482 moles; 1.26 equ.) of 1-octanol and 0.67 g of Lewatite K-2629 washed with acetone and dried under high vacuum (acidic ion-exchanger), the mixture was allowed to react over night at 140° C., and at the same time, the by-product ethanol formed was removed from the reaction mixture by sparging with an argon stream. The remaining volatile fractions were subsequently removed under high vacuum at 80° C. The product, 1-ethyl-3-methylimidazolium 1-octyl sulfate, was obtained as a medium-viscous, slightly yellow liquid in quantitative yield.

Provenance & Evidence