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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1442690Generated: November 2, 2026

1,2-Dichloroethane → HCID 11590207, compound

https://huagongshe.com/reaction/1442690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantAmmoniumHCID 223—
ReactantHCID 11597308HCID 11597308—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
ProductHCID 11590207HCID 115902077%

Reaction Steps

2-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzooxazole-5-carboxylic acid (150 mg, 0.343 mmol), DMAP (125 mg, 1.03 mmol) and EDC (99 mg, 0.514 mmol) and aqueous ammonium hydrroxide (1.0 mL, 30%) is reacted analogous to Example 2 to give the title product (10 mg, 7%). MS (ES) m/e: 437.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07659296B2
Source datasetuspto-grants-2010_02
ORD IDord-e4d59782bd5f4b2eac4ac1441572e647
Source noteuspto-grants-2010_02