Diethyl Ether → HCID 59166752, compound

Participants

Reaction Steps

4-(3-Chloro-phenylamino)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (Preparation 41, 155 mg, 0.456 mmol) was stirred in 4 M HCl in dioxan (4 ml) at 0° C. for 2 hours. Ether (4 ml) was added and the resultant white hygroscopic solid filtered off and dried in vacuo at 40° C. to give the title compound (90 mg, 60.3%).

Provenance & Evidence