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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1442966Generated: November 1, 2026

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester → HCID 59166749, compound

https://huagongshe.com/reaction/1442966

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 2734883—
Reactant2,3-Dihydro-1-benzofuran-6-olHCID 12236540—
ProductHCID 59166749HCID 5916674941.6%

Reaction Steps

The title compound was prepared from (2S,4R)-4-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl-ester 2-methyl ester and 2,3-dihydro-benzofuran-6-ol by the method of Preparation 14 in 41.6% yield as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07659305B2
Source datasetuspto-grants-2010_02
ORD IDord-77b981c7f77e49ad89ba8da0e5d6ee7c
Source noteuspto-grants-2010_02