2-Amino-4-methylthiazole → (2-Methyl-7-pyridin-3-yl-thiazolo[4,5-c]pyridin-4-yl)-(4-methyl-thiazol-2-yl)-amine

HRID 1443085Notes

Reaction equation

HRID 1443085 reaction equation
Cl[C:2]1[C:7]2[N:8]=[C:9]([CH3:11])[S:10][C:6]=2[C:5]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[CH:4][N:3]=1.[NH2:18][C:19]1[S:20][CH:21]=[C:22]([CH3:24])[N:23]=1>>[CH3:11][C:9]1[S:10][C:6]2[C:5]([C:12]3[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=3)=[CH:4][N:3]=[C:2]([NH:18][C:19]3[S:20][CH:21]=[C:22]([CH3:24])[N:23]=3)[C:7]=2[N:8]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 866124154-Chloro-2-methyl-7-pyridin-3-yl-thiazolo[4,5-c]pyridine

Product 1

HCID 16660736(2-Methyl-7-pyridin-3-yl-thiazolo[4,5-c]pyridin-4-yl)-(4-methyl-thiazol-2-yl)-amine

Procedure

The title compound, MS: m/e=340.1 (M+H+), was prepared in accordance with the general method of example 2, step 2 from 4-chloro-2-methyl-7-pyridin-3-yl-thiazolo[4,5-c]pyridine and 2-amino-4-methylthiazole.

Sources & evidence

ORD record
ord-9a1d3d544e264eaa9635069390a5be14
Source dataset
uspto-grants-2010_02
Patent number
US07659401B2

Reaction notes

Loading…