HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyrimidin-5-yl)boronic acid → (2-Methyl-7-pyrimidin-5-yl-thiazolo[4,5-c]pyridin-4-yl)-(2-methyl-thiazol-4-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyrimidin-5-yl)boronic acid | HCID 2795193 | — |
| Reactant | 2-Methyl-1,3-thiazol-4-amine | HCID 14772700 | — |
| Reactant | 4-Chloro-7-iodo-2-methylthiazolo[4,5-c]pyridine | HCID 76850478 | — |
| Product | (2-Methyl-7-pyrimidin-5-yl-thiazolo[4,5-c]pyridin-4-yl)-(2-methyl-thiazol-4-yl)-amine | HCID 16661049 | — |
Reaction Steps
The title compound, MS: m/e=341.0 (M+H+), was prepared in accordance with the general method of example 2, step 1 and step 2 from 4-chloro-7-iodo-2-methyl-thiazolo[4,5-c]pyridine (Example B), 5-pyrimidineboronic acid and 4-amino-2-methylthiazole (Example C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659401B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-7b0dd737598448688297391ae7b3eeda |
| Source note | uspto-grants-2010_02 |