HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanesulfonamide → Cyclopropanesulfonic acid [17-(7-methoxy-6-methyl-2-phenyl-quinazolin-4-yloxy)-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carbonyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanesulfonamide | HCID 15765418 | — |
| Reactant | 17-(7-Methoxy-6-methyl-2-phenyl-quinazolin-4-yloxy)-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carboxylic acid | HCID 68409390 | — |
| Product | Cyclopropanesulfonic acid [17-(7-methoxy-6-methyl-2-phenyl-quinazolin-4-yloxy)-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4,6*]octadec-7-ene-4-carbonyl]-amide | HCID 76593249 | 19% |
Reaction Steps
Reaction of the acid 120 (36 mg, 0.06 mmol) with cyclopropanesulfonic acid amide according to the procedure described in Example 53, gave the title compound (8 mg, 19%). MS (M−H)+ 703.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07659245B2 |
| Source dataset | uspto-grants-2010_02 |
| ORD ID | ord-bcd14314a7ef436986e289e35f7141ee |
| Source note | uspto-grants-2010_02 |